Miyezi isanu ndi inayi kuchokera pomwe idakhazikitsidwa ku US, Eisai ndi Biogen's Alzheimer's Leqembi ndi kukumana Kukana kwakukulu pakukhazikitsidwa kwake kofala, makamaka chifukwa cha kukayikira pakati pa madokotala ena za mphamvu zochizira matenda osokonekera aubongo.
Ngakhale kuti ndi mankhwala oyamba omwe atsimikiziridwa kuti amachepetsa kufalikira kwa matenda a Alzheimer's, kukayikira komwe kwazika mizu pakati pa azaumoyo pazakufunika kochiza matendawa kukuwonetsa kukhala chopinga chachikulu.
Akatswiri a matenda a Alzheimer poyambirira ankayembekezera zovuta zokhudzana ndi ndondomeko yomwe Leqembi ankafuna, yomwe imaphatikizapo mayesero owonjezera a matenda, kulowetsedwa kawiri pamwezi, ndi kufufuza muubongo nthawi zonse kuti awone zotsatira zomwe zingakhale zovuta. Zowonadi, zofunikira izi zathandizira kuti mankhwalawa asamagwiritsidwe ntchito pang'onopang'ono kuyambira pomwe adavomerezedwa ndi US Food and Drug Administration, zomwe zikuwonetseredwa ndi zokambirana ndi akatswiri 20 a minyewa ndi ma geriatrics kumadera osiyanasiyana aku US.
Malinga ndi a Reuters, madotolo asanu ndi awiri adaulula kukayikira kwawo kupereka mankhwala a Leqembi, akumakayikira za mphamvu ya mankhwalawa, mtengo wake, komanso kuopsa kwake. Kuphatikiza apo, gulu la akatswiri asanu ndi limodzi otsogola pantchitoyi lidawonetsa kuti "mankhwala osachiritsika" - lingaliro loti Alzheimer's ndi matenda osagonjetseka - ali ndi mphamvu yayikulu kuposa momwe amayembekezeredwa pochepetsa chidwi pakati pa madotolo achipatala, ma geriatrician, ndi akatswiri amisala. Kukayikira kumeneku kumakhudza kufunitsitsa kwawo kutumiza odwala kwa akatswiri okumbukira kuti akalandire chithandizo ndi Leqembi.
Akatswiri ena amanena kuti kukayikira pakati pa madokotala ena kungayambitsidwe ndi nthawi yayitali yokayikitsa yomwe inasokoneza mphamvu ya Alzheimer's protein beta amyloid kuti achepetse kukula kwa matendawa. Zotsatira zolimbikitsa za mayeso a Leqembi zisanachitike, ambiri azachipatala adawona kuti upangiri wa kafukufukuyu ndi wosapindulitsa.
Nkhawa zadzutsidwa ndi akatswiri ena azachipatala okhudza zotsatira za Leqembi, monga kutupa kwa ubongo ndi magazi, kuphatikizapo ndalama zomwe zimaperekedwa ndi mtengo wamtengo wapatali wa $ 26,500 pachaka, MRIs kawirikawiri, ndi kulowetsedwa kawiri pamwezi.
Leqembi anali mankhwala oyamba omwe amatsata amyloid kulandira chivomerezo chonse cha FDA atawonetsa kuchepa kwa 27% pakutsika kwa chidziwitso pakati pa odwala a Alzheimer's oyambilira panthawi ya mayeso azachipatala. Ngakhale cholinga choyambirira chothandizira anthu aku America 10,000 kumapeto kwa Marichi, ndi masauzande ochepa okha omwe adayamba kulandira chithandizo kumapeto kwa Januware, monga adanenera Eisai, yemwe wolankhulira wake adakana kupereka ziwerengero zosinthidwa.
Kulandira mankhwala atsopano, ngakhale omwe safuna kusintha kwakukulu muzachipatala, akuchedwa pang'onopang'ono. Kafukufuku wasonyeza kuti zingatenge zaka 17 kuti kafukufuku wachipatala akhale chizolowezi. Alzheimer's imakhudza anthu aku America opitilira 6 miliyoni, komabe ochepera theka la akatswiri amisala aku US amalimbikitsa Leqembi kwa odwala awo, malinga ndi kafukufuku wa Januware. sayansi wofufuza za msika Spherix Global Insights.
Written by Alius Noreika
