Likhoeli tse robong ka mor'a hore e hlahisoe US, moriana oa Alzheimer oa Eisai le Biogen Leqembi ke ho kopana le khanyetso e kholo ho amoheleheng ha eona ho atileng, haholo-holo ka lebaka la lipelaelo har'a lingaka tse ling mabapi le katleho ea ho phekola lefu lena le fokolisang la boko.
Leha e le setlhare sa pele se netefalitsoeng ho liehisa tsoelo-pele ea lefu la Alzheimer, lipelaelo tse metseng ka metso har'a bafani ba tsa bophelo bo botle mabapi le boleng ba ho alafa boemo bona li ipaka e le tšitiso e kholo.
Qalong litsebi tsa lefu la Alzheimer li ne li lebelletse liphephetso tse amanang le melaoana e boima ea Leqembi, e kenyelletsang liteko tse ling tsa tlhahlobo ea mafu, ho tšeloa habeli ka khoeli, le ho hlahloba boko kamehla ho beha leihlo litla-morao tse ka bang matla. Ehlile, litlhokahalo tsena li kentse letsoho tabeng ea ho sebetsa butle ha moriana ho tloha ha o amoheloa ke Tsamaiso ea Lijo le Lithethefatsi ea US, joalo ka ha ho pakoa ke lipuisano le lingaka tse 20 tsa methapo ea kutlo le lingaka libakeng tse fapaneng tsa US.
Ho ea ka Reuters, lingaka tse supileng li ile tsa senola ho qea-qea ha tsona ho fana ka lengolo la Leqembi, li bolela lipelaelo mabapi le katleho ea moriana ona, litšenyehelo tsa oona le likotsi tse amanang le oona. Ho feta moo, sehlopha sa litsebi tse tšeletseng tse etelletseng pele lefapheng lena li bontšitse hore "phekolo ea bofokoli" - maikutlo a hore Alzheimer's ke boemo bo ke keng ba hlōloa - e na le tšusumetso e kholo ho feta kamoo ho neng ho lebelletsoe ho fokotsa cheseho har'a lingaka tsa tlhokomelo ea mantlha, lingaka le lingaka tsa boko. Ho belaela hona ho ama boikemisetso ba bona ba ho fetisetsa bakuli ho litsebi tsa mohopolo bakeng sa kalafo e ka bang teng le Leqembi.
Litsebi tse ling li re ho tsilatsila ha lingaka tse ling ho ka bakoa ke nako e telele ea lipelaelo tse ileng tsa pupetsa matla a ho lebisa Alzheimer's protein beta amyloid ho liehisa tsoelo-pele ea lefu lena. Pele ho liphetho tse khothatsang tsa teko ea Leqembi, ba bangata lefapheng la bongaka ba ne ba nka hore tataiso ena ea lipatlisiso e se na litholoana.
Matšoenyeho a 'nile a hlahisoa ke litsebi tse ling tsa bongaka mabapi le litla-morao tsa Leqembi, tse kang ho ruruha boko le ho tsoa mali, ho phaella litšenyehelong tse amanang le theko ea selemo ea $26,500 ea selemo, li-MRIs khafetsa, le ho tšeloa habeli ka khoeli.
Leqembi e bile setlhare sa pele se shebaneng le li-amyloid ho fumana tumello e felletseng ea FDA kamora ho bonts'a phokotseho ea 27% ea ho theoha ha kelello har'a bakuli ba Alzheimer ba maemong a pele nakong ea liteko tsa bongaka. Leha ho na le sepheo sa pele sa ho phekola Maamerika a 10,000 mafelong a Hlakubele, ke ba likete tse 'maloa feela ba neng ba qalile kalafo mafelong a Pherekhong, joalo ka ha ho tlalehiloe ke Eisai, eo 'muelli oa hae a hanne ho fana ka lipalo tse ntlafalitsoeng.
Ho amoheloa ha litlhare tse ncha, esita le tse sa hlokeng liphetoho tse khōlō tšebetsong ea bongaka, ho lieha ka tsela e nyarosang. Lipatlisiso li bonts'itse hore ho ka nka lilemo tse 17 hore lipatlisiso tsa bongaka li fetohe tloaelo. Alzheimer's e ama Maamerika a fetang limilione tse 6, leha ho le joalo, lingaka tse ka tlase ho halofo tsa United States li khothaletsa Leqembi ho bakuli ba bona, joalo ka tlhahlobo ea bophelo ea Pherekhong. saense mofuputsi oa 'maraka Spherix Global Insights.
ngotsoeng ke Alius Noreika
