Mwedzi mipfumbamwe mushure mekutanga kuUS, Eisai uye Biogen's Alzheimer's drug Leqembi is kusangana Kupokana kwakakosha mukugamuchirwa kwayo kwakapararira, zvakanyanya nekuda kwekukahadzika pakati pevamwe vanachiremba nezve kugona kwekurapa chirwere ichi chehuropi chinopera simba.
Zvisinei nekuve mushonga wekutanga unoratidzwa kuti unonotsa kufambira mberi kweAlzheimer's, kusava nechokwadi kwakadzika pakati pevapi vehutano nezve kukosha kwekurapa mamiriro ari kuratidza kuve chipingamupinyi chikuru.
Vanamazvikokota veAlzheimer pakutanga vaitarisira matambudziko ane chekuita neprotocol yaLeqembi, iyo inosanganisira yekuwedzera ongororo, kuiswa kweviri pamwedzi, uye kuongorora uropi nguva dzose kuti vatarise zvingangove zvakakomba maside effects. Chokwadi, izvi zvinodiwa zvakakonzera kuti mushonga uyu utore zvishoma nezvishoma kubva pakutenderwa kwawakaitwa neUS Food and Drug Administration, sezvinoratidzwa nenhaurirano ne20 veneurologist uye geriatricians kumatunhu akasiyana eUS.
Sekureva kweReuters, vanachiremba vanomwe vakaburitsa pachena kusazeza kwavo kunyorera Leqembi, vachitaura kusava nechokwadi nezvekushanda kwemushonga, mutengo wawo, uye njodzi dzawainawo. Uyezve, boka renyanzvi nhanhatu dzinotungamira mundima dzakaratidza kuti "kurapa nihilism" - fungidziro yekuti Alzheimer's inzvimbo isingakundike - iri kuita zvakakosha kupfuura zvinotarisirwa mukudzikamisa kufarira pakati pevanachiremba vekutanga, mageriatricians, uye neurologist. Kusatenda uku kuri kukanganisa kuda kwavo kuendesa varwere kunyanzvi dzendangariro kuti vanorapwa naLeqembi.
Dzimwe nyanzvi dzinoti kusada pakati pevamwe vanachiremba kunogona kubva panguva yakareba yekusahadzika iyo yakavhara kushanda kwekunangana neAlzheimer's protein beta amyloid kuti inonoke kufambira mberi kwechirwere. Kusati kwaitika zvinokurudzira zvakabuda mukuyedza kweLeqembi, vazhinji vezvekurapa vaiona danho rekutsvaga iri serisina zvibereko.
Kunetseka kwakasimudzwa nevamwe vashandi vezvokurapa maererano nemigumisiro yeLeqembi, yakadai sekuzvimba kweuropi uye kubuda ropa, kunze kwemari inobatanidzwa ne $ 26,500 yemutengo wegore negore, nguva dzose MRIs, uye bi-monthly infusions.
Leqembi yaive yekutanga amyloid-yakananga mushonga kugamuchira yakazara FDA mvumo mushure mekuratidzira kudzikira kwe27% mukudzikira kwekuziva pakati pekutanga-danho reAlzheimer's panguva yekuedzwa kwekiriniki. Kunyangwe paine chinangwa chekutanga kurapa vanhu zviuru gumi vekuAmerica pakupera kwaKurume, zviuru zvishoma chete zvaive zvatanga kurapwa pakupera kwaNdira, sezvakataurwa naEisai, uyo mutauriri wake akaramba kupa huwandu hwakagadziridzwa.
Kugamuchirwa kwemishonga mitsva, kunyange iyo isingade kuchinja kukuru mune zvekurapa, inononoka zvakashata. Tsvagiridzo yakaratidza kuti zvinogona kutora avhareji yemakore gumi nemanomwe kuti tsvakiridzo yekiriniki ive yenguva dzose. Alzheimer's inobata vanhu vanopfuura mamirioni matanhatu vekuAmerica, asi vasingasviki hafu yevanachiremba vezveuropiyo vekuUS vari kukurudzira Leqembi kuvarwere vavo, sekuongororwa kwehupenyu hwaNdira. sciences muongorori wemusika Spherix Global Insights.
rakanyorwa Alius Noreika
