Ingilazi yewayini elibomvu idala ikhanda elibuhlungu, elingabangelwa izici ezihlukahlukene, enye yezimbangela eziyinhloko ama-histamines. I-histamines yizinhlanganisela zemvelo ezitholakala ewayinini, futhi iwayini elibomvu, ikakhulukazi, linamazinga aphezulu kunewayini elimhlophe. Uma esetshenzisiwe, ama-histamines angabangela ukungezwani komzimba kwabanye abantu, okuholela ezimpawu ezifana nekhanda elibuhlungu.
Iwayini elibomvu lithola umbala walo ocebile kanye nephunga elinamandla elivela esikhumbeni samagilebhisi esithintana nejusi yamagilebhisi ngesikhathi sokuvutshelwa. Lokhu kuthintana isikhathi eside kubangela ukugcwala okuphezulu kwezinhlanganisela, okuhlanganisa nama-histamine. Ama-histamines ayatholakala futhi esikhumbeni samagilebhisi futhi angakhululwa ngesikhathi sokuchotshozwa kwamagilebhisi kanye nokuvutshelwa. Kubantu abazwelayo kuma-histamines, ukusabela komzimba kulezi zinhlanganisela kungase kuhlanganise nokuphathwa yikhanda.
Ngaphezu kwalokho, iwayini elibomvu linenye into eyaziwa ngokuthi i-tyramine. I-Tyramine iyi-amino acid eyenzeka ngokwemvelo engenza imithambo yegazi iqine bese ivuleka, okungaholela ekuphathweni kwekhanda. Abanye abantu basengozini yokuthola imiphumela ye-tyramine futhi kubo ukusetshenziswa kwewayini elibomvu kungabangela ubuhlungu bekhanda. Enye into enomthelela ekhanda lewayini elibomvu ukuba khona kwama-sulfite. Ama-sulfite ama-compounds avame ukusetshenziswa njengezilondolozi ewayinini. Nakuba zenzeka ngokwemvelo ngezinga elithile, abenzi bewayini bavame ukwengeza ama-sulfite engeziwe ukuze balondoloze ubusha bewayini futhi bavimbele ukubola. Abanye abantu bayazwela kuma-sulfite, futhi lokhu kuzwela kungabonakala njengekhanda elibuhlungu noma i-migraines. Ukwengeza, okuqukethwe kotshwala ewayinini elibomvu kungase kubambe iqhaza ekubangeleni ubuhlungu bekhanda. Utshwala buyi-diuretic, okusho ukuthi kwandisa ukukhiqizwa komchamo, okuholela ekuphelelweni kwamanzi emzimbeni. Ukuphelelwa amanzi emzimbeni kungase kubangele ubuhlungu bekhanda, futhi lapho kuhlanganiswa nezinye izici ezifana ne-histamine ne-tyramine, kungandisa amathuba okuba nekhanda elibuhlungu elibangelwa iwayini.
Kubalulekile ukuqaphela ukuthi ukusabela komuntu ngamunye ewayini elibomvu kungase kuhluke. Izinto ezifana nezakhi zofuzo, impilo evamile, kanye nokuzwela komuntu siqu kudlala indima ebalulekile ekunqumeni ukuthi umuntu usabela kanjani kumakhemikhali atholakala ewayinini elibomvu. Kulabo abahlale bephathwa yikhanda ngemva kokuphuza iwayini elibomvu, kungase kube usizo ukuhlola ezinye izindlela ezine-histamine nama-sulfite aphansi noma uthintane nochwepheshe bezempilo ukuze uthole izimbangela ezithile futhi uthole izindlela zokudambisa izimpawu. Ukwengeza, ukuhlala u-hydrated nokuphuza iwayini ngokulinganisela kungasiza ekunciphiseni ubungozi bekhanda elihambisana nokusetshenziswa kwewayini elibomvu.
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