Kuyaziwa ukuthi inqwaba yotshwala idala umfutho wegazi ophezulu. Ucwaningo olwenziwa abacwaningi base-Linkoping University manje selukhombisa ukuthi ngisho nenani elincane lotshwala liyawunyusa umfutho wegazi. Abantu abasabela ngokuqinile kakhulu babonisa nezimpawu zokucindezeleka enhliziyweni.
I-liquorice - isithombe esinezithombe. Ikhredithi yesithombe: Pixabay (Ilayisensi ye-Pixabay yamahhala)
Uphuzo oludakayo lukhiqizwa empandeni yezitshalo zohlobo lwe-Glycyrrhiza futhi sekuyisikhathi eside lusetshenziswa njengekhambi lokwelapha kanye nokunambitheka. Kodwa-ke, kuyaziwa ukuthi ukudla i-liquorice nakho kungakhuphula umfutho wegazi. Lokhu kubangelwa ikakhulukazi into ebizwa ngokuthi i-glycyrrhizic acid ethinta ibhalansi yoketshezi lomzimba ngemiphumela ye-enzyme ezinso. Umfutho wegazi ophakeme wona ukhulisa ingozi yesifo senhliziyo nemithambo yegazi.
Kokubili i-European Union kanye ne-World Health Organization baphethe ngokuthi i-100 mg ye-glycyrrhizic acid ngosuku cishe iphephile ukudliwa kubantu abaningi. Kodwa abanye abantu badla ugologo kakhulu kunalokho. I-Swedish Food Agency ilinganise ukuthi amaphesenti angu-5 abantu baseSweden banokudla okungaphezulu kwaleli zinga.
Ingabe umkhawulo uphephile?
Ocwaningweni lwamanje, olushicilelwe ku I-American Journal of Clinical Nutrition, abacwaningi base-Linkoping University bafuna ukuhlola ukuthi umkhawulo oshiwo njengokungenzeka uphephile unjalo noma cha.
Akulula ukwazi ukuthi ingakanani i-glycyrrhizic acid ku-liquorice oyidlayo, njengoba ukugxila kwayo emikhiqizweni ehlukene yotshwala kuyahluka kakhulu. Lokhu kuhluka kungase kuncike ezintweni ezifana nemvelaphi, izimo zokugcinwa kanye nezinhlobo zezimpande ze-liquorice. Ngaphezu kwalokho, inani le-glycyrrhizic acid aliboniswa emikhiqizweni eminingi. Ucwaningo lweNyuvesi yase-Linkoping olokuqala olulinganise ngokucophelela inani le-glycyrrhizic acid ku-liquorice elahlolwa, kuyilapho lihlelwa ngokungahleliwe futhi lineqembu elilawulayo.
Wadla i-liquorice amasonto amabili
Ocwaningweni, abesifazane nabesilisa abangu-28 abaneminyaka engu-18–30 bayalwe ukuthi badle i-liquorice, noma umkhiqizo olawulayo owawungenalo noma yiluphi uphuzo oludakayo, phakathi nezikhathi ezimbili. Umkhiqizo olawulayo ubuqukethe i-salmiak, enikeza uphuzo olunosawoti ukunambitheka kwawo. I-liquorice yayinesisindo esingamagremu angu-3.3 futhi iqukethe u-100 mg we-glycyrrhizic acid, okungukuthi, inani elikhonjiswe njengelingase liphephe kubantu abaningi ukuba balidle nsuku zonke. Abahlanganyeli babelwa ngokungahleliwe ukuthi badle i-liquorice noma umkhiqizo wokulawula amasonto amabili, bathathe ikhefu amasonto amabili, bese bedla enye inhlobo amasonto amabili. Lokhu kwenza abacwaningi bakwazi ukuqhathanisa umphumela wazo zombili izinhlobo kumuntu oyedwa. Abahlanganyeli bocwaningo bacelwa ukuthi balinganise umfutho wegazi labo ekhaya nsuku zonke. Ekupheleni kwesikhathi ngasinye sokuthatha, abacwaningi balinganise amazinga amahomoni ahlukahlukene, ibhalansi kasawoti, nomthwalo wenhliziyo.
“Ocwaningweni sithole ukuthi ukuphuzwa kotshwala nsuku zonke obuno-100 mg glycyrrhizic acid kunyusa umfutho wegazi entsheni ephile saka. Lokhu bekungakaze kuboniswe ngenani elincane kangaka lotshwala,” kusho u-Peder af Geijerstam, umfundi ofundela ubudokotela eMnyangweni Wezempilo, Isayensi Yezokwelapha Nezokunakekela e-Linköping University, udokotela ojwayelekile, nombhali oholayo wocwaningo.
Lapho ababambiqhaza bedla utshwala, umfutho wegazi wabo wenyuka ngesilinganiso esingu-3.1 mmHg.
Ezinye zazizwela kakhulu
Abacwaningi baphinde balinganisa amahomoni amabili athintwa i-liquorice futhi alawula ibhalansi yoketshezi: i-renin ne-aldosterone. Amazinga akho kokubili ayancipha uma udla uphuzo oludakayo. Ikota yabahlanganyeli bocwaningo ababezwela kakhulu, ngokusekelwe emazingeni abo amahomoni e-renin kanye ne-aldosterone eyancipha kakhulu ngemva kokudla i-liquorice, nayo yazuza isisindo esincane, cishe ngenxa yokwanda koketshezi emzimbeni. Leli qembu futhi lalinamazinga aphakeme weprotheyini inhliziyo ewafihla kakhulu lapho idinga ukusebenza kanzima ukumpompa igazi emzimbeni, i-N-terminal pro-brain natriuretic peptide (NT-proBNP). Lokhu kuphakamisa ukukhuphuka kwevolumu yoketshezi kanye nomsebenzi wenhliziyo kubantu abazwela kakhulu emiphumeleni ye-liquorice.
"Imiphumela yethu inikeza isizathu sokuqapha kakhudlwana uma kukhulunywa ngezincomo kanye nokulebula ukudla okuqukethe utshwala," kusho uFredrik Nyström, uprofesa emnyangweni ofanayo, owayebhekele lolu cwaningo.
Ucwaningo luxhaswe ngokwesekwa, phakathi kokunye, i-Strategic Research Network in Circulation and Metabolism (LiU-CircM) e-Linköping University, The National Research School in General Practice at Umeå University, King Gustaf V kanye neQueen Victoria Freemason Foundation kanye neSifunda Östergötland. .
Isihloko: Umthamo ophansi wokudla kwansuku zonke we-licorice uthinta i-renin, i-aldosterone, nomfutho wegazi wasekhaya esivivinyweni esingahleliwe se-crossover, Peder af Geijerstam, Annelie Joelsson, Karin Rådholm kanye noFredrik Nyström, (2024). I-American Journal of Nutrition Clinic, Umq. 119 No. 3-682-692. Ishicilelwe ku-inthanethi ngomhla ka-20 Januwari 2024, doi: 10.1016/j.ajcnut.2024.01.011
Ibhalwe nguKarin Söderlund Leifler
Source: I-Linköping University
